Simultaneous Quantification of 30 Elements in the Mineral Chinese Medicine Quartz Album by ICP-MS for the Identification of Different Geogenesis

Background Quartz album is one of the mineral drugs commonly used in Chinese medicine. Different geogenesis led to differences its composition and thus affected clinical efficacy. Mineral medicines are mainly composed inorganic elements, including some heavy metals harmful so their quality control crucial safety. Materials Methods In this study, contents 30 elements 13 batches different origins were determined by inductively coupled plasma mass spectrometry (ICP-MS). Multiple chemometrics distinguish geogenesis. Results We found that top order content as follows: Al>Fe>Ca>K>Mg>Ti>Mn, all with greater than 100 µg/g. addition, ranges Pb, Cd, As, Hg, Cu 1.603–637.705, 0.011–1.387, 0.348–41.298, 0.033–10.877, 0.808–86.482 µg/g, respectively. albums produced Fengyang County, Anhui Province, had lowest metals. Correlation analysis showed there was a strong correlation among samples. Chemometrics analyze elemental content, results models be consistent could between Conclusion This study provided reference for safety application album.